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Heat Shock Protein 60 Antibodies Are Associated With a Risk Factor for Cardiovascular Disease in Bedridden Elderly Patients

2020

Made available in DSpace on 2020-12-12T02:12:50Z (GMT). No. of bitstreams: 0 Previous issue date: 2020-06-12 Frailty, in elderly people, represents multiple deficiencies in different organs and is characterized by decreased physiological reserves and greater vulnerability to stressors. Bedridden elderly, with cardiovascular disease (CVD), have a worse prognosis than non-bedridden patients. Heat-shock proteins (HSPs) are molecular chaperones that under physiological conditions facilitate the transport, folding and assembly of proteins. Serum HSP 60-kDa concentrations and their antibodies are increased, in response to non-physiological conditions, suggesting the involvement of HSPs and their …

0301 basic medicinemedicine.medical_specialtyDiseaseBiochemistry Genetics and Molecular Biology (miscellaneous)Biochemistry03 medical and health sciences0302 clinical medicineanti-HSP60 antibodycardiovascular diseaseInternal medicineHeat shock proteinmedicineElderly peoplerisk factorsMolecular BiosciencesRisk factorlcsh:QH301-705.5Molecular BiologyOriginal ResearchFramingham Risk Scorebiologybedridden elderlybusiness.industryPlasma levels030104 developmental biologylcsh:Biology (General)030220 oncology & carcinogenesisbiology.proteinHSP60AntibodybusinessHSP60
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